Dermagen Reports Successful Phase I/IIa Clinical Trial for Atopic Dermatitis |
|
DermaGen AB today announced that it has received promising results from a clinical Phase I/IIa study. DermaGen AB is developing a novel antimicrobial peptide (AMP) treatment for atopic dermatitis. Atopic dermatitis is a chronic inflammatory skin disease where dry skin and the skin’s weakened barrier function make patients susceptible to colonization by microorganisms, a triggering or exacerbating factor of the disease The AMP has shown a broad spectrum of activity and is both bactericidal and fungicidal. In the clinical trial, the company’s candidate drug clearly reached its primary objective, demonstrating a significant reduction of total microbes in eczemas compared to placebo. In addition to good safety and tolerability performance, the candidate drug also showed a trend towards improved eczema status. This is the first time a study has shown efficacy of AMPs for atopic dermatitis in man. Jørgen Thorball, Pergamum’s Chairman, stated, “DermaGen is a very exciting company with a strong technology platform. These promising clinical results go a long way towards establishing proof of concept within atopic dermatitis. They also strengthen the company’s position as it explores additional, first-in-class opportunities for the candidate drug and other compounds for the topical treatment of dermatological infections, such as impetigo and infected wounds and burns.” For further information, please contact: Jørgen Thorball, Chairman, Pergamum AB |
Download press release